Article
Higher glutathione transferase GSTM1 0/0 genotype frequency in young thyroid carcinoma patients.
Current medical research and opinion - 1 Jan 2003
Canbay Emel, Dokmetas Sebila, Canbay Ercan Ismet, Sen Metin, Bardakci Fevzi
Abstract excerpt
OBJECTIVE: Glutathione S-transferases (GSTs) comprise a large supergene family and detoxify a variety of endogenous and exogenous electrophilic compounds. Since many GSTs are polymorphic, there has been considerable interest in determining whether particular allelic variants are associated with altered risk for various disorders. RESEARCH DESIGN AND METHODS: In this study the association between the variant GSTM1...
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