Article
The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs.
Developmental cell - 1 May 2003
Abrahante Juan E, Daul Aric L, Li Ming, Volk Mandy L, Tennessen Jason M, Miller Eric A, Rougvie Ann E
Abstract excerpt
Temporal control of development is an important aspect of pattern formation that awaits complete molecular analysis. We identified lin-57 as a member of the C. elegans heterochronic gene pathway, which ensures that postembryonic developmental events are appropriately timed. Loss of lin-57 function causes the hypodermis to terminally differentiate and acquire adult character prematurely. lin-57 is hbl-1, revealing...
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