Article
The human marginal zone B cell.
Annals of the New York Academy of Sciences - 1 Apr 2003
Dono Mariella, Zupo Simona, Colombo Monica, Massara Rosanna, Gaidano Gianluca, Taborelli Giuseppe, Ceppa Paola, Burgio Vito L, Chiorazzi Nicholas, Ferrarini Manlio
Abstract excerpt
This study describes the features of the marginal zone (MZ) B cells of human tonsils and spleens and compares them with those of the follicular mantle (FM) B cells from the same tissues. The two B cell subpopulations displayed marked differences in phenotype, in response capacity to T cell-independent antigens and polyclonal B cell activators, and in presentation of antigens to T cells. FM B cells expressed...
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