Article
Genetic regulation of fibrin structure and function: complex gene-environment interactions may modulate vascular risk.
Lancet (London, England) - 26 Apr 2003
Lim Bernard C B, Ariëns Robert A S, Carter Angela M, Weisel John W, Grant Peter J
Abstract excerpt
BACKGROUND: Polymorphisms in the fibrinogen and factor XIII genes are associated with atherothrombotic risk, but clinical studies have produced inconsistent results and laboratory studies have not explained these findings. We aimed to investigate interactions between polymorphisms in the factor XIII and fibrinogen genes, fibrinogen concentrations, and other cardiovascular risk factors in relation to fibrin...
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