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Article

Functional analysis of the fibrinogen Aalpha Thr312Ala polymorphism: effects on fibrin structure and function.

Circulation - 13 May 2003

Standeven Kristina F, Grant Peter J, Carter Angela M, Scheiner Thomas, Weisel John W, Ariëns Robert A S

Abstract excerpt

BACKGROUND: The fibrinogen Aalpha Thr312Ala polymorphism occurs within the alphaC domain of fibrinogen, which is important for lateral aggregation and factor XIII-induced cross-linking of fibrin fibers. We have previously shown an association of Ala312 fibrinogen with poststroke mortality in subjects with atrial fibrillation and with pulmonary embolism in subjects with venous thrombosis. METHODS AND RESULTS: We...

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PMID: 12707238
DOI: 10.1161/01.CIR.0000066690.89407.CE

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SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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