Article
Disparity between association and linkage analysis for HNF1A G319S in type 2 diabetes in Canadian Oji-Cree.
Journal of human genetics - 1 Jan 2000
Hegele R A, Hanley A J, Zinman B, Harris S B, Anderson C M
Abstract excerpt
In parallel experiments designed to find the genetic determinants of type 2 diabetes in Oji-Cree, we identified several linked chromosomal regions, using genomic scanning, in addition to a private diabetes-associated mutation, namely HNF1A G319S, using candidate gene sequencing. The genome scan did not identify the region harboring HNF1A as being linked with diabetes. Also, the HNF1A mutation, when used directly...
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