Article
Analysis of a shared pancreatic cancer antigen recognized by an HLA-A*2601-restricted cytotoxic T-lymphocyte clone.
Pancreas - 1 May 2003
Kashiwagi Kiyoteru, Ikeda Hideyuki, Hirohashi Yoshihiko, Yamamoto Masayuki, Idenoue Satomi, Hirai Itaru, Kamiguchi Kenjiro, Tamura Yasuaki, Torigoe Toshiko, Wada Yshimasa, Hirata Koichi, Sato Noriyuki
Abstract excerpt
INTRODUCTION: We have generated HLA-A*2601-restricted CD8+ CTL clones against an autologous pancreatic cancer cell line. AIMS: To characterize the antigen expressed on the cancer cells. METHODOLOGY: We assessed cytotoxic activities and cytokine production of these CTL clones reacting against cancer cell lines that stably or transiently expressed the HLA-A*2601 gene. RESULTS: These CTL clones recognized 4 of 10...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.