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Article

Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians.

Diabetes - 1 May 2003

Kovacs Peter, Lehn-Stefan Angela, Stumvoll Michael, Bogardus Clifton, Baier Leslie J

Abstract excerpt

FOXC2 is a winged helix gene that has been shown to counteract obesity, hypertriglyceridemia, and diet-induced insulin resistance in rodents. Therefore, FOXC2 was analyzed as a candidate gene for susceptibility to type 2 diabetes in Pima Indians. Four variants were identified by sequencing the coding region, as well as 638 bp of the 5' region and 300 bp of the 3' region of the gene. Two single nucleotide...

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Identifiers

PMID: 12716768
DOI: 10.2337/diabetes.52.5.1292

Genes

FOXC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians.PMID 12716768Read ↗

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FOXC2 Is a Winged Helix Gene that Counteracts Obesity, Hypertriglyceridemia, and Diet-Induced Insulin ResistanceSemantic proximity Read ↗

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.Semantic proximity Read ↗

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