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Article

A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension.

Journal of hypertension - 1 May 2003

Rayner Brian L, Owen E Patricia, King Judy A, Soule Steven G, Vreede Heleen, Opie Lionel H, Marais David, Davidson James S

Abstract excerpt

OBJECTIVE: To determine the relationship between R563Q, a mutation of the renal epithelial sodium channel, and hypertension. METHODS: Hypertensive patients with low renin and aldosterone, hypokalemia or resistant hypertension were selected for DNA analysis. Genomic DNA encoding the C-terminal domain of the epithelial sodium channel beta subunit from hypertensives and controls was amplified by polymerase chain...

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Source

Identifiers

PMID: 12714866
DOI: 10.1097/00004872-200305000-00016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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