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Article

Mobilization of hematopoietic stem cells during homeostasis and after cytokine exposure.

Blood - 15 Aug 2003

Abkowitz Janis L, Robinson Abigail E, Kale Sujata, Long Michael W, Chen Jing

Abstract excerpt

We created parabiotic mice, joining ROSA26 and PeP3b animals, to study the trafficking of hematopoietic stem cells (HSCs) from marrow to blood and their return to marrow. The transfer of HSCs was assayed by secondary marrow transplantation and was 1.0% to 2.5% after 3, 6, 8, and 12 weeks. Thus, HSC homeostasis is primarily maintained by the retention of stem cells derived from replication events within the...

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Identifiers

PMID: 12714498
DOI: 10.1182/blood-2003-01-0318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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