Article
Hybridization enhancement using cavitation microstreaming.
Analytical chemistry - 15 Apr 2003
Liu Robin Hui, Lenigk Ralf, Druyor-Sanchez Roberta L, Yang Jianing, Grodzinski Piotr
Abstract excerpt
Conventional DNA microarray hybridization relies on diffusion of target to surface-bound probes, and thus is a rate-limited process. In this paper, a micromixing technique based on cavitation microstreaming principle that was developed to accelerate hybridization process is explained. Fluidic experiments showed that air bubbles resting on a solid surface and set into vibration by a sound field generated steady...
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