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Microfluidic and Turbulent Mixing for mRNA LNP Vaccines

1 Sept 2025

Abstract excerpt

Using lipid nanocarriers to deliver the mRNA of a specific antigen to immune cells is a powerful innovative approach to rapidly develop new safe and effective vaccines. Understanding and optimizing the mixing process necessary for mRNA lipid nanoparticles (LNPs) is the focus of this review. The first objective is to review the fundamentals of microfluidic and turbulent fluid-mixing basics needed to understand the...

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PMID: 41012485
DOI: 10.3390/pharmaceutics17091148

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