Article
Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth.
Nature - 6 Jul 2000
Zhu G, Spellman P T, Volpe T, Brown P O, Botstein D, Davis T N, Futcher B
Abstract excerpt
There are about 800 genes in Saccharomyces cerevisiae whose transcription is cell-cycle regulated. Some of these form clusters of co-regulated genes. The 'CLB2' cluster contains 33 genes whose transcription peaks early in mitosis, including CLB1, CLB2, SWI5, ACE2, CDC5, CDC20 and other genes important for mitosis. Here we find that the genes in this cluster lose their cell cycle regulation in a mutant that lacks...
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