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Article

SEK1-dependent JNK1 activation prolongs cell survival during G-Rh2-induced apoptosis.

Biochemical and biophysical research communications - 2 May 2003

Ham Young-Mi, Chun Kwang-Hoon, Choi Joon-Seok, Kim Dong-Hyun, Lee Seung-Ki

Abstract excerpt

We provide here evidence that c-Jun N-terminal protein kinase 1 (JNK1) activity is differentially up-regulated during apoptosis of SK-HEP-1 cells after treatment with ginsenoside Rh2 (G-Rh2). The G-Rh2-mediated JNK1 activation that occurred for the first 10-30min was associated with SEK1 activity, but thereafter, the sustained activation was associated not with SEK1 activity, but with proteolytic cleavage of...

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PMID: 12711323
DOI: 10.1016/s0006-291x(03)00591-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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