Article
Gene expression patterns in AIDS versus non-AIDS-related diffuse large B-cell lymphoma.
Experimental and molecular pathology - 1 Apr 2003
Patrone Lisa, Henson Sarah E, Teodorovic Jelena, Malone Cindy S, French Samuel W, Wall Randolph, Teitell Michael A
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is more prevalent and more often fatal in AIDS patients compared to immune-competent individuals. Potential explanations for these differences include distinct tumorigenic mechanisms and/or altered cellular microenvironments. We previously discovered that the TCL1 (T-cell leukemia-1) proto-oncogene is expressed in a high proportion of AIDS-DLBCL compared to DLBCL cases and...
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