Article
Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population.
Metabolism: clinical and experimental - 1 Jul 2001
Yamada A, Shoji T, Tahara H, Emoto M, Nishizawa Y
Abstract excerpt
Paraoxonase is a high-density lipoprotein (HDL)-bound esterase that hydrolyzes various organophosphorus compounds and protects low-density lipoprotein (LDL) against accumulation of lipid peroxides. Paraoxonase activity is strongly affected by the polymorphism of the paraoxonase gene (PON1) at position 192. In addition, the enzyme activity shows a great variation within each genotype, although the underlying...
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