European versus Asian differences for the associations between paraoxonase-1 genetic polymorphisms and susceptibility to type 2 diabetes mellitus.

doi:10.1111/jcmm.13453

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Article

European versus Asian differences for the associations between paraoxonase-1 genetic polymorphisms and susceptibility to type 2 diabetes mellitus.

Journal of cellular and molecular medicine - 1 Mar 2018

Luo Jian-Quan, Ren Huan, Liu Mou-Ze, Fang Ping-Fei, Xiang Da-Xiong

Abstract excerpt

Many studies have examined the associations between paraoxonase-1 (PON1) genetic polymorphisms (Q192R, rs662 and L55M, rs854560) and the susceptibility to type 2 diabetes mellitus (T2DM) across different ethnic populations. However, the evidence for the associations remains inconclusive. In this study, we performed a meta-analysis to clarify the association of the two PON1 variants with T2DM risk. We carried out...

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Alleles
Aryldialkylphosphatase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Asian People

Diabetes Mellitus, Type 2

Genetic Predisposition to Disease

Polymorphism, Single Nucleotide

Risk Factors

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 29314660
DOI: 10.1111/jcmm.13453
PMCID: PMC5824408

Genes

PON1

Variants

rs662
rs662

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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