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Article

painless, a Drosophila gene essential for nociception.

Cell - 18 Apr 2003

Tracey W Daniel, Wilson Rachel I, Laurent Gilles, Benzer Seymour

Abstract excerpt

We describe a paradigm for nociception in Drosophila. In response to the touch of a probe heated above 38 degrees C, Drosophila larvae produce a stereotypical rolling behavior, unlike the response to an unheated probe. In a genetic screen for mutants defective in this noxious heat response, we identified the painless gene. Recordings from wild-type larval nerves identified neurons that initiated strong spiking...

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Identifiers

PMID: 12705873
DOI: 10.1016/s0092-8674(03)00272-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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