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Article

The ankyrin repeat domain of the TRPA protein painless is important for thermal nociception but not mechanical nociception.

PloS one - 1 Jan 2012

Hwang Richard Y, Stearns Nancy A, Tracey W Daniel

Abstract excerpt

The Drosophila TRPA channel Painless is required for the function of polymodal nociceptors which detect noxious heat and noxious mechanical stimuli. These functions of Painless are reminiscent of mammalian TRPA channels that have also been implicated in thermal and mechanical nociception. A popul...

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Identifiers

PMID: 22295071
DOI: 10.1371/journal.pone.0030090
PMCID: PMC3266251

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22295071-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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