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Article

Candida albicans RHO1 is required for cell viability in vitro and in vivo.

FEMS yeast research - 1 May 2002

Smith Susan E, Csank Csilla, Reyes Guadalupe, Ghannoum Mahmoud A, Berlin Vivian

Abstract excerpt

In Saccharomyces cerevisiae, Rho1p plays an important role in cell wall integrity by regulating beta-1,3-glucan synthase, Pkc1p and the actin cytoskeleton. To determine the physiological role of Rho1p in the dimorphic fungus Candida albicans, the major human fungal pathogen, we constructed mutants that conditionally express Rho1p from the glucose-repressible phosphoenolpyruvate carboxykinase promoter (pPCK1). We...

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Source

Identifiers

PMID: 12702298
DOI: 10.1111/j.1567-1364.2002.tb00075.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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