Candida albicans Rho-type GTPase-encoding genes required for polarized cell growth and cell separation.

doi:10.1128/EC.00201-06

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Article

Candida albicans Rho-type GTPase-encoding genes required for polarized cell growth and cell separation.

Eukaryotic cell - 1 May 2007

Dünkler Alexander, Wendland Jürgen

Abstract excerpt

Rho proteins are essential regulators of morphogenesis in eukaryotic cells. In this report, we investigate the role of two previously uncharacterized Rho proteins, encoded by the Candida albicans RHO3 (CaRHO3) and CaCRL1/CaRHO4 genes. The CaRHO3 gene was found to contain one intron. Promoter shutdown experiments using a MET3 promoter-controlled RHO3 revealed a strong cell polarity defect and a partially...

Topics

Candida albicans
Cell Polarity
Cytokinesis
Fungal Proteins
Gene Deletion
Gene Expression
Genes, Fungal
Hyphae
Models, Biological
Molecular Sequence Data
Morphogenesis
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Protein Transport

Recombinant Fusion Proteins

Sequence Analysis, DNA

Sequence Homology, Nucleic Acid

rho GTP-Binding Proteins

Source

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Identifiers

PMID: 17351079
DOI: 10.1128/EC.00201-06
PMCID: PMC1899239

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