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Article

Immunogenetic heterogeneity in single-system and multisystem langerhans cell histiocytosis.

Pediatric research - 1 Jul 2003

Bernstrand Cecilia, Carstensen Henrik, Jakobsen Bodil, Svejgaard Arne, Henter Jan-Inge, Olerup Olle

Abstract excerpt

Langerhans cell histiocytosis is a rare disease with an unknown etiology and poorly understood pathogenesis. Immunologic, viral, and proliferative clonality causes have all been considered. To determine whether Langerhans cell histiocytosis and its two main subgroups, single-system and multisystem disease, are associated with HLA-A, -B, -Cw, or -DR alleles, a total of 84 patients <15 y of age at the time of...

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PMID: 12700369
DOI: 10.1203/01.PDR.0000069844.50684.7D

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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