Article
Langerhans cell histiocytosis.
Advances in anatomic pathology - 1 Nov 1998
Herzog K M, Tubbs R R
Abstract excerpt
Langerhans cell histiocytosis (LCH) is a rare clonal disorder that consists of single or multiple mass lesions composed of cells with an abnormal Langerhans cell phenotype. Its etiology remains unknown, despite extensive searches for evidence of consistent cytogenetic abnormalities, gene rearrangements, or viral genomes. Similarly, the pathogenesis of the disease is enigmatic, although the altered expression of...
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