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Article

Association of both Langerhans cell histiocytosis and Erdheim-Chester disease linked to the BRAFV600E mutation.

Blood - 14 Aug 2014

Hervier Baptiste, Haroche Julien, Arnaud Laurent, Charlotte Frédéric, Donadieu Jean, Néel Antoine, Lifermann François, Villabona Carles, Graffin Bruno, Hermine Olivier, Rigolet Aude, Roubille Camille, Hachulla Eric, Carmoi Thierry, Bézier Maud, Meignin Véronique, Conrad Marie, Marie Laurence, Kostrzewa Elise, Michot Jean-Marie, Barete Stéphane, Taly Valerie, Cury Karine, Emile Jean-François, Amoura Zahir

Abstract excerpt

Histiocytoses are a group of heterogeneous diseases that mostly comprise Langerhans cell histiocytosis (LCH) and non-LCH. The association of LCH with non-LCH is exceptional. We report 23 patients with biopsy-proven LCH associated with Erdheim-Chester disease (ECD) (mixed histiocytosis) and discus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 24894769
DOI: 10.1182/blood-2013-12-543793

Genes

ECD
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24894769-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Association of both Langerhans cell histiocytosis and Erdheim-Chester disease linked to the BRAFV600E mutation.PMID 24894769Read ↗

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