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Article

Differentiating skin-limited and multisystem Langerhans cell histiocytosis.

The Journal of pediatrics - 1 Nov 2014

Simko Stephen J, Garmezy Benjamin, Abhyankar Harshal, Lupo Philip J, Chakraborty Rikhia, Lim Karen Phaik Har, Shih Albert, Hicks M John, Wright Teresa S, Levy Moise L, McClain Kenneth L, Allen Carl E

Abstract excerpt

OBJECTIVE: To identify features associated with multisystem involvement and therapeutic failure in patients with skin Langerhans cell histiocytosis (LCH). STUDY DESIGN: We reviewed medical records of 71 consecutive patients with LCH with skin involvement evaluated at Texas Children's Hospital and analyzed clinical features, laboratory results, and the presence of circulating cells with the BRAF-V600E mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histiocytosis, Langerhans-Cell

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Source

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Identifiers

PMID: 25441388
DOI: 10.1016/j.jpeds.2014.07.063
PMCID: PMC4254414

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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