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Article

Is monosomy 5 an uncommon aberration? Fluorescence in situ hybridization reveals translocations and deletions in myelodysplastic syndromes or acute myelocytic leukemia.

Cancer genetics and cytogenetics - 15 Apr 2003

Bram Susanne, Swolin Birgitta, Rödjer Stig, Stockelberg Dick, Ogärd Inger, Bäck Hans

Abstract excerpt

Acquired loss of material from chromosome 5 in bone marrow cells is common in myelodysplastic syndromes (MDS) and acute myelocytic leukemia (AML). In this study, we have applied fluorescence in situ hybridization (FISH) analyses with probes for the three regions 5p15.2, 5q31, 5q33-q34, and whole chromosome 5 painting probes (WCP 5) to investigate what further information could be gained regarding the cytogenetic...

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Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytogenetic Analysis

Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Myeloid, Acute

Share to Monosomy

Share to Myelodysplastic Syndromes

Share to Translocation, Genetic

Source

Identifiers

PMID: 12699885
DOI: 10.1016/s0165-4608(02)00836-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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