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Article

Predicting susceptibility to norovirus GII.4 by use of a challenge model involving humans.

The Journal of infectious diseases - 1 Nov 2012

Frenck Robert, Bernstein David I, Xia Ming, Huang Pengwei, Zhong Weiming, Parker Susan, Dickey Michelle, McNeal Monica, Jiang Xi

Abstract excerpt

BACKGROUND: GII.4 is the predominant norovirus genotype worldwide. Challenge models involving humans have shown the association of human histo-blood group antigens (HBGAs) and susceptibility to infection with Norwalk virus (GI.1 norovirus), but the association of HBGAs and infection with other noroviruses is based on results of epidemiological studies. We performed the first GII.4 challenge study involving humans...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22927452
DOI: 10.1093/infdis/jis514

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ABO

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