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Article

Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett’s oesophagus

11 Apr 2003

Abstract excerpt

BACKGROUND AND AIMS: Characterisation of the underlying molecular mechanisms that promote Barrett's progression may ultimately lead to identification of potential predictive genetic markers that classify patients' malignant risk. In an attempt to understand these causative pathways, fluorescence in situ hybridisation (FISH) was used in this study to determine when specific genetic alterations arise during...

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Identifiers

PMID: 12692043
DOI: 10.1136/gut.52.5.623

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