Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA Study.

Stroke - 1 May 2003

Kohara Katsuhiko, Fujisawa Michiko, Ando Fujiko, Tabara Yasuharu, Niino Naoakira, Miki Tetsuro, Shimokata Hiroshi

Abstract excerpt

BACKGROUND AND PURPOSE: Silent brain infarcts (SBI) and white matter lesions are relatively common neuroimaging findings, especially in the elderly population. The genetic background for SBI and white matter lesions in a large Japanese general population was investigated. METHODS: Subjects were recruited from participants in the National Institute for Longevity Sciences, Longitudinal Study of Aging. Genotyping of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebral Infarction
Share to Glucose Intolerance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hyperhomocysteinemia

Share to Hyperlipidemias

Share to Life Style

Share to Longitudinal Studies

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Oxidoreductases Acting on CH-NH Group Donors

Source

Identifiers

PMID: 12690212
DOI: 10.1161/01.STR.0000069163.02611.B0

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA Study.PMID 12690212Read ↗

Silent stroke: pathogenesis, genetic factors and clinical implications as a risk factor.Semantic proximity Read ↗

Elevated plasma homocysteine levels and risk of silent brain infarction in elderly people.Semantic proximity Read ↗

Association of methylenetetrahydrofolate reductase (MTHFR 677C>T and 1298A>C) polymorphisms and haplotypes with silent brain infarction and homocysteine levels in a Korean population.Semantic proximity Read ↗

Effect of Methylenetetrahydrofolate Reductase (MTHFR) gene mutations and oxidative stress in silent brain infarctionSemantic proximity Read ↗

Genetic effect of MTHFR C677T, A1298C, and A1793G polymorphisms on the age at onset, plasma homocysteine, and white matter lesions in Alzheimer's disease in the Chinese population.Semantic proximity Read ↗

Effect of methylenetetrahydrofolate reductase gene polymorphisms and oxidative stress in silent brain infarction.Semantic proximity Read ↗

Natural history of silent lacunar infarction: 10-year follow-up of a community-based prospective study of 0.5 million Chinese adultsSemantic proximity Read ↗

Correlation between total homocysteine and cerebral small vessel disease: A Mendelian randomization study.Semantic proximity Read ↗

Association of methylenetetrahydrofolate reductase C677T polymorphism with lacunar infarction: A systematic review and meta-analysis.Semantic proximity Read ↗

The association of MTHFR C677T variant with increased risk of ischemic stroke in the elderly population: a meta-analysis of observational studies.Semantic proximity Read ↗

Association between homocysteine and white matter hyperintensities in asymptomatic intracranial arterial stenosis: results from a population-based studySemantic proximity Read ↗

MTHFR and risk of stroke and heart disease in a low-folate population: a prospective study of 156 000 Chinese adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.