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Article

TCR V beta 8+ T cells prevent development of toxoplasmic encephalitis in BALB/c mice genetically resistant to the disease.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2003

Kang Hoil, Liesenfeld Oliver, Remington Jack S, Claflin Jennifer, Wang Xisheng, Suzuki Yasuhiro

Abstract excerpt

BALB/c are genetically resistant to development of toxoplasmic encephalitis (TE) when infected with Toxoplasma gondii, whereas CBA/Ca mice are susceptible. We compared TCR Vbeta chain usage in lymphocytes infiltrated into brains between these animals following infection. TCR Vbeta8(+) cells were the most frequent T cell population in brains of infected, resistant BALB/c mice, whereas TCR Vbeta6(+) T cells were...

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PMID: 12682259
DOI: 10.4049/jimmunol.170.8.4254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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