Role of Salmonella typhimurium Mn-superoxide dismutase (SodA) in protection against early killing by J774 macrophages.

doi:10.1128/iai.63.5.1739-1744.1995

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Article

Role of Salmonella typhimurium Mn-superoxide dismutase (SodA) in protection against early killing by J774 macrophages.

Infection and immunity - 1 May 1995

Tsolis R M, Bäumler A J, Heffron F

Abstract excerpt

The Salmonella typhimurium gene for Mn-cofactored superoxide dismutase (sodA) was cloned by complementation of an Escherichia coli sodA sodB mutant for growth on minimal medium. Sequence analysis revealed an open reading frame of 618 bp encoding a polypeptide with 97% identity to E. coli SodA. A S. typhimurium sodA mutant was created by allelic exchange and tested for the ability to survive in the murine...

Topics

Amino Acid Sequence
Animals
Bacterial Proteins
Base Sequence
Cell Line
Cloning, Molecular
Escherichia coli
Genes, Bacterial
Iron Deficiencies
Macrophages
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Repressor Proteins

Salmonella Infections

Salmonella typhimurium

Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 7729880
DOI: 10.1128/iai.63.5.1739-1744.1995
PMCID: PMC173218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7729880-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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