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Article

Interleukin 10 haplotype associated with increased risk of hepatocellular carcinoma.

Human molecular genetics - 15 Apr 2003

Shin Hyoung Doo, Park Byung Lae, Kim Lyoung Hyo, Jung Ji Hyun, Kim Jun Yeon, Yoon Jung Hwan, Kim Yoon Jun, Lee Hyo-Suk

Abstract excerpt

Interleukin 10 (IL10) is a powerful Th-2 cell cytokine produced by lymphoid cells that exerts its functions by inhibiting macrophage/monocyte and T-cell lymphocyte replication and secretion of inflammatory cytokines (IL1, TNFA, TGFB, IL6, IL8 and IL12). Genetic association analysis of a well-characterized HBV cohort revealed that one of IL10 haplotypes, IL10-ht2, was strongly associated with hepatocellular...

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Identifiers

PMID: 12668613
DOI: 10.1093/hmg/ddg104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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