Article
IL-10 Polymorphisms and Haplotypes Predict Susceptibility to Hepatocellular Carcinoma Occurrence in Patients with Hepatitis C Virus Infection from Northeast India.
Viral immunology - 1 Jan 2000
Barooah Prajjalendra, Saikia Snigdha, Kalita Manas Jyoti, Bharadwaj Rituraj, Sarmah Preeti, Bhattacharyya Mallika, Goswami Bhabadev, Medhi Subhash
Abstract excerpt
Chronic hepatitis C virus (HCV) infection leads to variable outcomes, ranging from prolonged slow hepatic damage leading to cirrhosis, and hepatocellular carcinoma (HCC). Polymorphism in cytokines IL-10 and IL-12 that impact the immune response to HCV infection may play a role in determining this outcome. This study was aimed to determine if polymorphisms in IL-10 and IL-12B contribute to HCV susceptibility and...
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