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Article

Pathogenesis of split-hand/split-foot malformation.

Human molecular genetics - 1 Apr 2003

Duijf Pascal H G, van Bokhoven Hans, Brunner Han G

Abstract excerpt

Split-hand/split-foot malformation (SHFM), also known as ectrodactyly, is a congenital limb malformation, characterized by a deep median cleft of the hand and/or foot due to the absence of the central rays. SHFM may occur as an isolated entity or as part of a syndrome. Both forms are frequently found in association with chromosomal rearrangements such as deletions or translocations. Detailed studies of a number...

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Identifiers

PMID: 12668597
DOI: 10.1093/hmg/ddg090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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