Insights into the pathogenesis and treatment of split/hand foot malformation (cleft hand/foot)

Abstract excerpt

Cleft hand or split hand foot malformation is a sequence of phenotypes, from a minor shortening of the central digit to a complete absence of the third ray and in the most severe cases, absence of two, three or four rays. It is a rare but spectacular presentation usually involving both hands and feet. Inheritance is mostly autosomal dominant but sporadic cases without family history are also reported, resulting...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Congenital limb and hand anomalies
• Share to Genomic variations and chromosomal abnormalities
• Share to Prenatal Screening and Diagnostics