Article
Association of the androgen receptor CAG repeat polymorphism with Alzheimer's disease in men.
Neuroscience letters - 10 Apr 2003
Lehmann D J, Butler H T, Warden D R, Combrinck M, King E, Nicoll J A R, Budge M M, de Jager C A, Hogervorst E, Esiri M M, Ragoussis J, Smith A D
Abstract excerpt
We examined the CAG repeat polymorphism in exon 1 of the androgen receptor (AR) in an Oxford cohort of 150 cases (101 men) of definite or probable Alzheimer's disease (AD) and 190 elderly controls (140 men). We found that short alleles (< or = 20 CAG repeats) were associated with AD (adjusted odds ratio = 2.5, 95% confidence intervals: 1.2-5.0) in men, but not in women. This association appeared stronger in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
