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Article

The complex life of WT1.

Journal of cell science - 1 May 2003

Wagner Kay-Dietrich, Wagner Nicole, Schedl Andreas

Abstract excerpt

The Wilms' tumour gene, WT1, encodes a zinc-finger transcription factor that is inactivated in a subset of Wilms' tumours. Mutation analysis in human patients and genetic experiments in mice have revealed that WT1 has a role much wider than just tumour suppression. Alternative splicing, RNA editing, and the use of alternative translation initiation sites generate a multitude of isoforms, which seem to have...

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Identifiers

PMID: 12665546
DOI: 10.1242/jcs.00405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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