Article
High anti-Helicobacter pylori antibody seropositivity associated with the combination of IL-8-251TT and IL-10-819TT genotypes.
Helicobacter - 1 Apr 2003
Hamajima Nobuyuki, Katsuda Nobuyuki, Matsuo Keitaro, Saito Toshiko, Hirose Kaoru, Inoue Manami, Zaki Toshiro Take, Tajima Kazuo, Tominaga Suketami
Abstract excerpt
BACKGROUND: Helicobacter pylori induces inflammation of gastric mucosa regulated by several interleukins. This study examined associations between anti-Helicobacter pylori immunoglobulin G antibody seropositivity and functional polymorphisms of interleukin-8 T-251 A and interleukin-10 T-819C. MATERIALS AND METHODS: The subjects were 454 health check-up examinees (126 males and 328 females) without a history of...
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