Article
Polyamines reduce paraquat-induced soxS and its regulon expression in Escherichia coli.
Cell biology and toxicology - 1 Feb 2003
Jung I L, Kim I G
Abstract excerpt
Polyamines, ubiquitous polycationic compounds, are involved in many cellular responses and relieve paraquat-induced cytotoxicity in Escherichia coli. We constructed a new E. coli mutant strain, JIL528, which is deficient in the biosynthesis of both putrescine and spermidine, to examine the physiological role of polyamines under oxidative stress caused by paraquat. Putrescine and spermidine downregulate the...
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