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Article

Paraquat toxicity is increased in Escherichia coli defective in the synthesis of polyamines.

Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990

Minton K W, Tabor H, Tabor C W

Abstract excerpt

We have shown that toxicity of paraquat for Escherichia coli is increased over 10-fold in strains defective in the biosynthesis of spermidine compared to isogenic strains containing spermidine. The increased sensitivity of these spermidine-deficient mutants to paraquat is eliminated by growth in...

Topics

Aerobiosis
Anaerobiosis
Escherichia coli
Genotype
Kinetics
Mutation
Paraquat
Polyamines
Putrescine
Spermidine
Time Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2181453
DOI: 10.1073/pnas.87.7.2851
PMCID: PMC53789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2181453-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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