Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Mar 2003

Rudhard York, Kneussel Matthias, Nassar Mohammed A, Rast Georg F, Annala Alexander J, Chen Philip E, Tigaret Cezar M, Dean Isabel, Roes Juergen, Gibb Alasdair J, Hunt Stephen P, Schoepfer Ralf

Abstract excerpt

Precise refinement of synaptic connectivity is the result of activity-dependent mechanisms in which coincidence-dependent calcium signaling by NMDA receptors (NMDARs) under control of the voltage-dependent Mg2+ block might play a special role. In the developing rodent trigeminal system, the pattern of synaptic connections between whisker-specific inputs and their target cells in the brainstem is refined to form...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Stem
Share to Calcium Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Targeting

Share to Genes, Lethal

Share to Magnesium

Share to N-Methylaspartate

Share to Receptors, N-Methyl-D-Aspartate

Share to Respiration

Source

Open in PubMed Open full text

Identifiers

PMID: 12657691
PMCID: PMC6742004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling.PMID 12657691Read ↗

Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice.Semantic proximity Read ↗

NMDA receptor-dependent refinement of somatotopic maps.Semantic proximity Read ↗

Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice.Semantic proximity Read ↗

Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear.Semantic proximity Read ↗

Mutation of Npr2 leads to blurred tonotopic organization of central auditory circuits in mice.Semantic proximity Read ↗

Gain-of-function nature of Cav1.4 L-type calcium channels alters firing properties of mouse retinal ganglion cells.Semantic proximity Read ↗

Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus.Semantic proximity Read ↗

Mice with genetically modified NMDA and AMPA receptors.Semantic proximity Read ↗

Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene.Semantic proximity Read ↗

Trigeminal ganglion neuron subtype-specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine.Semantic proximity Read ↗

NR1 knockdown reveals CA1 injury during a developmental period of high seizure susceptibility despite reduced seizure activity.Semantic proximity Read ↗

Local Inhibitory Dynamics Underpin Temporal Integration and Functional Segregation between Barrels and Septa in the Mouse Barrel CortexSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.