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Article

Isolation of antibiotic hypersusceptibility mutants of Acinetobacter spp. by selection for DNA release.

Antimicrobial agents and chemotherapy - 1 Apr 2003

Lee Hyunwoo, Vázquez-Laslop Nora, Klyachko Katya A, Neyfakh Alex A

Abstract excerpt

Isolation of bacterial mutants hypersusceptible to antibiotics can reveal novel targets for antibiotic potentiators. However, identification of such mutants is a difficult task which normally requires laborious replica plating of thousands of colonies. The technique proposed here allows for the positive selection of genetic knockout mutants leading to hypersusceptibility. This technique, designated SDR (selection...

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Identifiers

PMID: 12654657
DOI: 10.1128/AAC.47.4.1267-1274.2003
PMCID: PMC152507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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