Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling the impact of interferon alfa treatment on liver fibrosis progression in chronic hepatitis C: a dynamic view. The Multivirc Group.

Gastroenterology - 1 Feb 1999

Sobesky R, Mathurin P, Charlotte F, Moussalli J, Olivi M, Vidaud M, Ratziu V, Opolon P, Poynard T

Abstract excerpt

BACKGROUND & AIMS: Impact of hepatitis C treatment has never taken into account the dynamics of fibrosis progression. This study assessed the impact of interferon on liver fibrosis progression in patients with chronic hepatitis C according to 3-month aminotransferase activity response. METHODS: We recruited 287 patients, 185 treated and 102 control, with paired biopsy specimens. Before follow-up, the fibrosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Progression

Share to Genotype

Share to Models, Statistical

Share to Multivariate Analysis

Share to Risk Factors

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 9922319
DOI: 10.1016/s0016-5085(99)70135-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling the impact of interferon alfa treatment on liver fibrosis progression in chronic hepatitis C: a dynamic view. The Multivirc Group.PMID 9922319Read ↗

Impact of common risk factors of fibrosis progression in chronic hepatitis C.Semantic proximity Read ↗

Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C.Semantic proximity Read ↗

Role of hepatitis C virus genotype 3 in liver fibrosis progression--a systematic review and meta-analysis.Semantic proximity Read ↗

Disease progression in chronic hepatitis C: modifiable and nonmodifiable factors.Semantic proximity Read ↗

Hepatitis C virus genotypes and hepatic fibrosis regulate 24-h decline of serum hepatitis C virus RNA during interferon therapy in patients with chronic hepatitis C.Semantic proximity Read ↗

Fibrosis in chronic hepatitis C acquired in infancy: is it only a matter of time?Semantic proximity Read ↗

Genetic Polymorphisms of IL28B and PNPLA3 Are Predictive for HCV Related Rapid Fibrosis Progression and Identify Patients Who Require Urgent Antiviral Treatment with New Regimens.Semantic proximity Read ↗

Progression to advanced liver fibrosis in HIV-HCV-coinfected patients and prioritization of new hepatitis C therapies.Semantic proximity Read ↗

The impact of fibrosis and steatosis on early viral kinetics in HCV genotype 1-infected patients treated with Peg-IFN-alfa-2a and ribavirin.Semantic proximity Read ↗

Early on-treatment viral load and baseline METAVIR score: improved prediction of sustained virological response in HCV genotype 1 patients.Semantic proximity Read ↗

Prediction of Fibrosis Progression Rate in Patients with Chronic Hepatitis C Genotype 4: Role of Cirrhosis Risk Score and Host Factors.Semantic proximity Read ↗

The changing burden of hepatitis C virus infection in the United States: model-based predictions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.