Article
ER retention may play a role in sorting of the nuclear pore membrane protein POM121.
Experimental cell research - 1 Apr 2003
Imreh G, Maksel D, de Monvel J B, Brandén L, Hallberg Einar
Abstract excerpt
Integral membrane proteins of the nuclear envelope (NE) are synthesized on the rough endoplasmic reticulum (ER) and following free diffusion in the continuous ER/NE membrane system are targeted to their proper destinations due to interactions of specific domains with other components of the NE. By studying the intracellular distribution and dynamics of a deletion mutant of an integral membrane protein of the...
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