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Association of caffeine intake and CYP1A2 genotype with ovarian cancer.

Nutrition and cancer - 1 Jan 2003

Goodman Marc T, Tung Ko-Hui, McDuffie Katharine, Wilkens Lynne R, Donlon Timothy A

Abstract excerpt

Coffee and caffeine consumption has been associated with ovarian cancer risk in several epidemiological studies. CYP1A2 is a key enzyme in the metabolism of coffee and in the activation of heterocyclic aromatic compounds that may be carcinogenic. Data from a preliminary investigation conducted in Hawaii of 164 epithelial ovarian cancer cases and 194 controls were used to examine the hypothesis that coffee and...

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Identifiers

PMID: 12925300
DOI: 10.1207/S15327914NC4601_03

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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