Article
Expression of adrenomedullin and its receptor by chondrocyte phenotype cells.
Biochemical and biophysical research communications - 28 Mar 2003
Chosa Etsuo, Hamada Hiroaki, Kitamura Kazuo, Kuwasako Kenji, Yanagita Toshihiko, Eto Tanenao, Tajima Naoya
Abstract excerpt
For clarifying a process of de-differentiation in culturing chondrocytes, the present study was undertaken to investigate the secretion of adrenomedullin (AM) by chondrocyte phenotype cells and whether or not AM effects this proliferation in a cAMP-dependent fashion. Chondrocyte phenotype cells expressed AM and the AM receptor, and secreted high concentration of AM into the culture medium. When added to cultures,...
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