Article
Gain in 1q is a common abnormality in phyllodes tumours of the breast.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology - 1 Jan 2003
Jee Kowan J, Gong Gyungyub, Ahn Sei Hyun, Park Jeong Mi, Knuutila Sakari
Abstract excerpt
We studied DNA copy number changes by CGH and allelic imbalance (AI) on 3p by LOH analysis on 22 phyllodes tumours (PT) of the breast in order to gain insight into the genetic basis of tumour progression in PT. Copy number changes were observed in 14 cases (63%). Gain in 1q with 1q21-23 as the minimal overlapping area was seen in 12 cases (55%). The gain was observed both in benign and malignant tumours. Our...
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