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Article

Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components.

The American journal of pathology - 1 Mar 2000

Sawyer E J, Hanby A M, Ellis P, Lakhani S R, Ellis I O, Boyle S, Tomlinson I P

Abstract excerpt

Phyllodes tumors are fibroepithelial mammary lesions that tend to behave in a benign fashion but may undergo sarcomatous transformation. A study of clonality in these tumors has suggested that the epithelial component is polyclonal, but the stroma is monoclonal, and thus forms the neoplastic component of the lesion. In this study microsatellites on chromosome 1q and chromosome 3p were assessed for allelic...

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Identifiers

PMID: 10702425
DOI: 10.1016/S0002-9440(10)64977-2
PMCID: PMC1876863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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