Article
Oxidative stress in ataxia telangiectasia.
Redox report : communications in free radical research - 1 Jan 2003
Watters Dianne J
Abstract excerpt
Ataxia telangiectasia is one of a group of recessive hereditary genomic instability disorders and is characterized by progressive neurodegeneration, immunodeficiency and cancer susceptibility. Heterozygotes for the mutated gene are more susceptible to cancer and to ischaemic heart disease. The affected gene, ATM (ataxia telangiectasia mutated), has been cloned and codes for a protein kinase (ATM), which...
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