Article
Transcriptional activities of cholecystokinin promoter haplotypes and their relevance to panic disorder susceptibility.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2003
Ebihara Mitsuru, Ohba Hisako, Hattori Eiji, Yamada Kazuo, Yoshikawa Takeo
Abstract excerpt
We previously identified a polymorphic compound short tandem repeat (STR) in the 5'-regulatory region of the cholecystokinin (CCK) gene, and showed that when the STRs were classified into three groups based on length and linkage disequilibrium behavior with neighboring variants, the medium class allele was significantly associated with panic disorder. The present study examined the transcriptional activity of the...
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